Myofibroblasts Close the Wound, Then They Have to Leave
Myofibroblasts close oral wounds and stabilize the implant site. They have to disappear on schedule: when they stay, the scar becomes fibrosis.
Bone Biology
18 articles
sorted by most recent
Do Sharpey's Fibers Regulate Bone Metabolism?
Jean Aaron's review proposes a periosteum–Sharpey–endosteum continuum: a poorly mineralized collagen III network that regulates bone. The one we strip.
Buried Alive: The Osteoblast's Three Fates
The osteoblast builds bone, then meets three fates: apoptosis, the quiet of a lining cell, or being buried alive to become an osteocyte.
Diabetes, Prediabetes, and Implants. No Problem. But Check Your Glycated Hemoglobin.
Diabetes and prediabetes do not rule out implants: HbA1c (glycated hemoglobin) counts. Thresholds, peri-implantitis, and your diabetologist.
Chronic Stress and Periodontal Bone Loss — The Mechanism
Chronic stress consumes the bone around the teeth through the HPA axis, cortisol, and the collapse of IL-10. The molecular mechanism, and 4 ways to break it.
BNC2: How the Periosteum Wakes Up Stem Cells After a Fracture
A transcription factor called BNC2 opens the chromatin of periosteal stem cells and enables bone healing. When it's missing, the fracture doesn't consolidate.
The menopause-gum axis that medicine is rediscovering
Osteoporosis and periodontitis share biology and risk factors: meta-analysis on 19,611 patients and the critical four-year window after menopause.
The dental X-ray that could save your bones: how AI turns the OPT into an osteoporosis screening tool
AI analyzes dental panoramic X-rays and detects osteoporosis with 88% sensitivity. Two 2024–2025 meta-analyses redefine what a routine dental visit can detect.
Occlusal Trauma Does Not Prevent Periodontal Healing
Lindhe and Ericsson (1976) demonstrate that occlusal trauma does not impair healing after periodontal surgery, provided plaque is removed.
Vertical Implant Positioning: Every Connection Has Its Correct Depth
Bone-level, tissue-level, conical connection: the correct depth changes with connection type. Why getting it wrong causes bone resorption.
Bone Metabolism Mediators: Molecules with 1000 Functions
RANKL, RANK and OPG: the molecules that govern bone remodeling and immunity — and why they matter in periodontics and implant dentistry.
Alveolar bone: what it is, why it is lost, and how you rebuild volume
Alveolar bone holds your teeth and your implants. After extraction it shrinks in predictable ways. Anatomy, causes, and what the data say about rebuilding.
Implant Failure Is Rare: Watch Immunity, Metabolism, and Medications
Dental implant failure biology: macrophages, metabolism, and drugs. A risk-factor guide to protect osseointegration.
Malpositioned Dental Implant: Risks, Symptoms and Solutions
A malpositioned dental implant loses 0.25 mm of bone per 10° of angular error. Symptoms, when it's fixable, and when it must be removed.
Myofibroblasts: what they are and why they decide whether an implant heals
What myofibroblasts do after an implant: the difference between osseointegration and fibrointegration, and how to keep an implant from failing.
The Bone's Neural Network: The Osteocyte Connectome
The osteocyte connectome: the lacunocanalicular network that coordinates bone remodeling, mechanics and implant osseointegration.
Bone Remodeling: The Biological Cycle That Decides Implant Fate
Osteoclasts resorb, osteoblasts build, osteocytes coordinate: how bone remodeling works and why it determines dental implant success.
Help! I'm Manola and I have periodontitis
Manola has periodontitis. When is root planing enough, when is surgery needed, and why trust between patient and dentist quietly decides the outcome.